Which Chains Does SanctionsAI Cover? [2026 Answer]

SanctionsAI screens OFAC listed wallets across EVM chains, Bitcoin, and Tron, with native Base and USDC support.

TL;DR

TL;DR: SanctionsAI screens the 947 OFAC-listed crypto wallets across EVM chains such as Ethereum, Base, Arbitrum, and Optimism, plus Bitcoin and Tron, with native Base and USDC support for agent payments.

Chains and wallet coverage

The dataset tracks 947 OFAC-listed crypto wallets, synced hourly, so a listed address is caught regardless of the chain it lives on. EVM chains like Ethereum, Base, Arbitrum, and Optimism share a common address format, while Bitcoin and Tron use their own, and the screening logic handles each format correctly.

Base and USDC for agent payments

SanctionsAI integrates natively with Base and USDC, which are common rails for AI agent payments. Because x402, AP2, ACP, and Coinbase AgentKit move money but do not screen, SanctionsAI adds the missing check: a single HTTP call under 100 ms that returns ALLOW or BLOCK before the transfer settles.

Why chain coverage matters

A sanction is only as good as the screen that catches it. If an agent pays a listed wallet on an unscreened chain, the violation still happens and penalties still start at $356,000 per violation. Screening every chain the agent can reach closes that gap and keeps the compliance posture consistent across rails. Keeping the dataset synced hourly means a newly listed address is caught on the next check, no matter which chain the agent is about to use. Coverage has to follow the agent wherever it can spend.